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50%
of EGFR NSCLC patients on 1st line TKIs develop EGFR resistance mutations (p.T790M) [1].

LiquidSCREEN Lung is a polymerase chain reaction (PCR) blood test. It detects EGFR mutations and monitors changes to detect resistance mutations in Non-Small Cell Lung Cancer (NSCLC) patients.
The test can be used at:
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initial diagnosis to inform treatment selection
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follow-up for relapse or resistance monitoring
Available internationally outside the USA.
Gene List
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Sensitizing targets:
Exon 18: G719A, G719C, G719S
Exon 19: E746_A750del, L747_P753delinsS, L747_A750delinsP, L747_T751del
Exon 21: L858R, L861Q
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Resistance targets:
T790M
Downloads
References:
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Kobayashi, S. et al. N Engl J Med. 352(8):786-792, 2005.
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